Region 2 has had a complete Angel set for a few years now, but there hasn't been mention of a Region 1 release until now.
Our retail friends have told us that Fox is working on a complete series set for release on October 30. Details are very slim right now, but the suggested retail price for the 5 season set will be $149.98. There's no word on whether this set will include a bonus disc like the Buffy set had (R2 didn't have one, so chances are R1 won't have one either).
Stay tuned for more details when they're made available.